Addison’s disease, also known as hypoadrenocorticisim, is a condition that affects one or both of a dog’s adrenal glands, which are located just above the kidneys. Anything that damages the adrenal glands can trigger Addison’s disease. Dogs with this disorder don’t make enough adrenal hormones, which are critical to almost every aspect of bodily function. This causes circulating levels of glucose, potassium, sodium and chloride to become imbalanced, leading to dehydration and severe problems with vital organs, especially the heart. Affected dogs feel lousy, especially when they are under stress. They experience belly pain, nausea, vomiting, diarrhea, weakness, depression and other unpleasant symptoms, which typically come in waves. They may collapse for no apparent reason. Owners should be tuned in to the signs of Addison’s disease, so that they can get effective treatment for their beloved companions as soon as possible.