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The Dentistry Service of the University of Pennsylvania Veterinary Hospital is currently recruiting cats with oral stomatitis for a pilot study to evaluate the effectiveness of a new drug when injected into oral lesions. Knowledge gained from this study may provide an advancement in the treatment of feline stomatitis, and possibly similar conditions seen in humans. We are seeking ten cats with bilateral caudal stomatitis to be enrolled as a pilot to evaluate the potential for future studies.

Feline stomatitis is a poorly understood inflammatory disease of the oral mucosal linings which causes pain and suffering in domestic cats. Symptoms of oral pain include decreased appetite, vocalizing when eating, yawning or opening the mouth, and drooling. Severe chronic inflammation is seen in the gums and adjacent soft tissues around the teeth and in the back of the mouth, making it difficult to chew and swallow. Full-mouth extraction is currently the treatment of choice, which does provide significant benefit in approximately 80% of affected cats. However, approximately 20% of cats that underwent surgical extractions have continued inflammation and pain.

Eligibility
Criteria Include:

Cats
must be deemed to be otherwise healthy based on physical
examination and blood work.

Cats
must be previously diagnosed with bilateral caudal mucositis which has been unresponsive to other treatments, including full-mouth (or nearly full-mouth)
extractions.

Enrollment will finish May 15, 2012 or when 10 cats have been enrolled.


If
you are interested in enrolling a patient for this study, or would like more information, please contact the Veterinary Clinical Investigations Center at 215-573-0302 or vcic@vet.upenn.edu

avatar

CatSpert11

In Cats

Hi, I have 2 female cats ages 2 and 4, and one male cat who is about to turn 12.  My concern is with the girls.  My boyfriend and I moved in together almost a year ago.  I already owned Simon and Sophia and he owned Haylee.  Simon is not the issue because he is the most layed back cat you will ever meet.  Haylee was very neglected as a kitten and saved by my boyfriend.  Sophia is feisty and likes things to be her way.  We took our time and did everything we could to introduce them gradually.  We used Feliway and it seemed to have an adverse effect on Sophia.  We kept each in a different room and used blankets and toys to exchange each other's scent.  We had them play on either side of the door and rewarded with treats.  We let each cat have a chance to roam the remainder of the house on their own.  We opened the door just a little to let them start peeking at each other.  Finally, we let them have free rein of the house.  However, we are not so pleased with the relationship they currently have, stalking each other, hissing and growling, sneaking up on each other.  Things improved but are not great.  Haylee is also trying to adjust to having me.  Her abuser was a female so she is apprehensive but we are getting their.  I just feel bad that I can't show her the same affection as I do Simon and Sophia...maybe that plays a part in all of this?


So we are about to move again.  I was wondering if I should repeat the process of introducing them.  If so, should I do anything differently?  How long should this take?  The benefit to moving is everyone will have more space now! ANY advice would be greatly appreciated! 

Thanks!  
Hilary, Simon, Sophia, and Haylee

This has been going on one month.  My tenant died and her cat is hiding in a very inaccesable spot.  She found a hole in a closet and now hides in the frame work of the upstairs apt.  Trapping her with food, in a humain trap has been a complete failure. She has been existing on only the small pieces of food I leave to tempt her to the food in the trap release.  She never goes near it.  I have three traps.  I do leave out water. She uses her litter box in the middle of the night so I do know she is alive.  Please help.  I have pulled out all the walls that would give me access to her but no luck.  If she dies she is going to die where I can't get to her.  What else do I do????  I am a cat lover with five cats of my own.  This has me in tears.  

Hello!My 15 year poodle has prostate cancer and has been on treatement for almost a year.As of now he can,t move its tail for urination  and poop.Is there any prostetueses to help hold tail up?Thanqs

avatar

Dooger1995

In Dogs

Caty is from the dog rescue I volunteer with. It's really bothering me that we don't have the slightest idea of what breeds Caty is to tell potential adopters. I recently started thinking she might be a Pit Bull Terrier/Lab mix, but something for those two breeds is NOT lining up. She has to have something else too. Border Collie? I don't know :P

When Caty first came to us, she weighed a healthy 35 lbs. She's been in a couple foster homes and each time she has gained a couple pounds. She just came back from a foster home (they had her for about 3 months) and she has gained at least 15 lbs. Caty now weighs a hefty 60 lbs for such a small statured dog. Definitely needs to lose some weight now that she's back in our director's hands.

Caty is approximately 7 years old. She has a very short glossy brown and white coat. Her tail is like a hook and she has a long nose. Her body is compact and square in proportion. She has a deep chest and high set rose ears. Her bark is kind of raspy and high pitched. She is very mellow and very smart. She is also very athletic. She is really sweet and sensitive and attaches to her people really quick. She's great with other dogs and kids. She likes to chase cats.

What breeds do you think Caty has in her?


Thanks!

There are specific factors we teach a Dog to learn Swimming by instinct.
Sniffing, for instance, occasionally in embarrassing places. Barking,
too, and begging for foods scraps are also downloaded onto dogs’ inner
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Then there’s swimming. It appears so integral to getting a canine that
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How to teach Dog to Swim



1.Take the canine to an place where there is not lots of noise. This
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if there is truly lots of music and movement nearby.



2.Put the lifejacket inside the dog. While it is not required, it
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3.Enter the pool or shallow lake. once the canine is learning to swim
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Continually put him within pool at the similar area and help him walk
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4.Hold the dog's midsection and hindquarters and permit him to paddle
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5.Continue the lesson for an additional 10 minutes. Use rewards to show
very good habits and speak utilizing an upbeat and good voice.



6.Show the canine the best way to exit the pool or shallow lake. This is
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7.Wash the canine away with shampoo after the swimming lessons. Dry out
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How to teach Dog to learn Swimming video

I have recently adopted a Russian Blue rescue cat, he was left alone for a very long period without food, apart from being very thin, he is a wonderful cat, full of love and fun and I am setting about feeding him up and giving him a lot of fuss!  Only problem I have come across is he doesn't seem to sleep at night, instead he will meow loudly through the night whether I let him in the bedroom or not.  Is there any advice you can offer as to why he is doing this? I appreciate this breed is very intelligent, I have shown him his litter tray and toys and food which he has remembered all and uses frequetly but he doesn't seem to be interested in his bed and I am not getting a wink of sleep.  He clearly wants to be around me a lot and is very affectionate, other than craving attention, any ideas why he meow's so loudly and contstantly at night? Thanks.

I have cat that I had to bottle feed from a kitten cause his mother was run over.  He was a few weeks old, and my mothers cat was hit by a car, leaving 4 kittens behind.  They were not going to worry about the one i took cause he was blind.  We took him home, bottle fed him, and about 3 months later, his eyes cleared up and he is able to see!!!  We have had problems with him since he was a kitten with not always using the litter box.  As he has gotten older, he is better, but he still refuses to use it all the time.  He will pick different places all over the house, and as we get him to stop in one place, he just finds another "favorite place" to go.   We have had him for 2 years.  He is nutered and declawed, but my husband is so beyond done with finding poo all over.  PLEASE help me so we can keep my little kitty! 

   Both cats saw our Mobile vet friday for annual exam and shots.  Mickey a short hair grey male tabby cat of 3 yr walked into the cat carrier with no problem. As soon as the door closed he went nuts.  Vet sprayed him with some thing that was suppose to help him calm down.  It did not. 

   Back into the house we let him go in the bedroom where his safe spot is.  Since then when he spots his house mate of three yrs he starts hissing, growl, hair goes up and he swats at Sasha ( black/tan short hair female) and then runs.  She at frist tryed to touch noises but now gos into attack mode.  We have a full ongoing war.  and they are fully clawed.

   We have now set up space just for Mickey in the bedroom/bath and keeping the door close ... feeding etc by himself.... any suggests on how to go forward would be very welcome ... this is very stress full on everyone in the house...

    He has all ways ran and hid when someone came to the door.  But with everyone in the house specialy  his with his playmate Sasha he has been loving, playful no other problems ....  

avatar

kristen

In Dogs

 Bella is a Great Dane. She would have been 7 in December. I am so lost with out her my heart breaks and can not stop thinking of her the pain is unreal I need to be at peace with this. I have gone many hours searching of why this happen or what it was that caused her to die. Bella was a active Great Dane she had a half sister she died at the age of 5 we had to put her down she was unable to walk and she lost so much weight she was very ill my heart breaks from that as well. Bella  loved her sister and they were always together we never seen Bella grieve from sassy's death so we just thought with our support she would e fine which it seemed she was. she continued her everyday living not different we work so she was alone  but she always had our attention she would lay on the couch and beds with us my kids loved her she would run around the house and just leave chasing the kids as they would jump in the pool Bella was a healthy great Dane which is why i am on here trying to get answers. Bella was up to date on shots. I noticed about a month or less ago that she looked like she was getting thinner i was unsure because it was a slow weight loss then it sounded as she would cough it was loud like she was clearing her throat or something she did that on and off for a month which i thought it was nothing it happen  the most in the evening and usually after she ate or just out of the blue. she started eating less and still was drinking my husband and i came home from work as usual let he in from outside and we fed her like usual nothing was different however she started that coughing and then seemed like she was trying to vomit so we put her out side and then she came back in and kept repeating it for like an hour So she finally laid on the floor with feet out in front head up nothing different but she was in a spot where she would never lay it was behind the recliner so i went up to her and covered her with a blanket and rubbed her and talked to her and my husband and i discussed she needed to go to the vet the next day. She then got up and laid in another spot then we all went to bed we just thought she was sick she wasn't crying or showing any type of pain we just thought she was under the weather. I hate myself for going to bed that night and not staying with her. My husband woke me up at 2am and told me she had passed during the night. I am so heart broken I feel this is my fault she should have taken her somewhere that night it just didn't seem like it was an emergency at the time but she was dead beside the bed on a blanket her rib cage seem extended. she just looked like she was sleeping but she was stiff and was not moving we have 3 kids and both work we didn't have the money to find out what caused her death we buried her at 2:30am next to her sister. This is heart breaking I hate this pain I cant stop thinking was when she was pacing around in the bedroom was she trying to get our attention for help we just told her to lay down :( we didn't think anything. Did she go fast was she in a silent pain was she scared so many things are tormenting me and I am so lost with out her it hasn't been a year sense sassy our other Dane got put down. This is just really hard she was more then just a dog she was our baby and our family. I am looking for any kind of advice thoughts. Thanks everyone I am lost.

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