Introduction
Hip Dysplasia, Collie Eye Anomaly (CEA), and epilepsy are considered the primary genetic diseases of concern in the breed at this time. Elbow Dysplasia or Osteochondritis, deafness, and hypothyroidism may also occur in the breed.
Collie Eye Anomaly
Collie Eye Anomaly (CEA) is a congenital, inherited eye disease affecting Border Collies, but is sometimes mistaken for conjunctivitis and sometimes affects other breeds involving the retina, choroid, and sclera. In Border Collies it is generally a mild disease and rarely impairs vision significantly. There are now DNA tests available for CEA that can ensure breeders will not produce affected pups.
Neuronal Ceroid Lipofuscinosis
Neuronal Ceroid Lipofuscinosis (NCL) is a rare but serious disease. NCL results in severe neurological impairment and early death. Afflicted dogs rarely survive beyond two years of age. There is no treatment or cure, but a DNA test is now available to detect carriers as well as affected dogs.
Trapped Neutrophil Syndrome
Trapped Neutrophil Syndrome (TNS) is a hereditary disease that inhibits the release of neutrophils produced in the bone marrow into the blood stream. Because this is an autoimmune-deficiency disease affected puppies present a variety of symptoms>. Once thought to be rare, it is now believed to be responsible for many cases of "fading puppies".